Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
ProRoot MTA
- Development stage
- Phase 3
- Lead developer
- Dentsply Sirona
- Modality
- Implantable Devices → Device-based Delivery → Drug Delivery Systems
- Administration
- Intradental, Endodontic, Intracanal
01
Overview
ProRoot MTA is a dental root repair material composed primarily of mineral trioxide aggregate. It is designed to seal pathways between the root canal system and surrounding tissues, significantly reducing bacterial migration and promoting healing. The material sets in the presence of moisture due to its hydrophilic properties, forming a strong impermeable barrier that supports tissue regeneration and stimulates new cementum formation over the restored interface. Its high biocompatibility makes it suitable for various endodontic procedures including apexification (apical plug), repair of root perforations during root canal therapy, treatment of internal resorption, as a root-end filling material, direct pulp capping agent, and pulpotomy in pediatric patients. It is antimicrobial but non-toxic to human cells and exhibits low solubility with high radiopacity[1][2][4][5][6][8][10].
- Brand names
- ProRoot MTA
- Other names
- Mineral Trioxide AggregateProRoot Mineral Trioxide AggregateProRoot MTA Root Canal Repair Material
02
Targets
PGN (Peptidoglycan)
Beyond the preview
Go deeper on ProRoot MTA.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on ProRoot MTA.