Drug intelligence / Profile preview

ProscaVax

Development stage
Unknown
Lead developer
OncBioMune Pharmaceuticals
Modality
Cytokines & Interferons → Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration
Intradermal
01

Overview

**ProscaVax** is an investigational therapeutic cancer vaccine developed by OncBioMune Pharmaceuticals for prostate cancer. The product combines prostate-specific antigen with the immunostimulatory cytokines interleukin-2 and granulocyte-macrophage colony-stimulating factor. It is intended to induce PSA-directed antitumor immune responses while IL-2 supports T-cell activation and proliferation and GM-CSF promotes antigen-presenting-cell recruitment and activation. ProscaVax has been evaluated by intradermal administration in patients with PSA-recurrent hormone-naive or hormone-independent prostate cancer and in a Phase 2 study in treatment-naive clinically localized prostate cancer managed with active surveillance.

Brand names
ProscaVax
Other names
PSA/IL-2/GM-CSF vaccineprostate-specific antigen + interleukin-2 + granulocyte-macrophage colony-stimulating factor
02

Targets

IL-2R (Interleukin-2/interleukin-15 receptor complex)CSF2R (Granulocyte-macrophage colony-stimulating factor receptor)PSA (Puromycin-sensitive aminopeptidase)

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