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ProstaFluor
- Development stage
- Unknown
- Lead developer
- Vanderbilt University Medical Center
- Modality
- Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Small Molecules
- Administration
- Intravenous
01
Overview
**ProstaFluor** is an experimental diagnostic drug, specifically an antibody-photosensitizer conjugate designed for targeted detection and possibly therapy of prostate cancer. It acts by inhibiting both **KLK3 (Prostate-specific antigen, PSA)** and **PSMA (Prostate-specific membrane antigen)**, which are highly expressed in prostate cancer cells. The drug utilizes antibody targeting to bind selectively to these prostate cancer markers, and incorporates a fluorescent or photosensitizer moiety ("fluor"), making it suitable for use as a diagnostic dye in imaging or potentially for theranostic applications, such as image-guided surgery or targeted phototherapy.
- Brand names
- ProstaFluor
- Other names
- ProstaFluor
02
Targets
PSMA (Prostate-specific membrane antigen)
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