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Protexin Restore

Development stage: Unknown
Lead developer: ADM Protexin
Modality: Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
Administration: Oral

Overview

Protexin Restore is a multi-strain synbiotic developed by Protexin Healthcare (a brand of ADM Protexin Limited). It is a live biotherapeutic product consisting of a mixture of seven probiotic bacterial strains—*Lactobacillus casei*, *Lactobacillus rhamnosus*, *Streptococcus thermophilus*, *Bifidobacterium breve*, *Lactobacillus acidophilus*, *Bifidobacterium infantis*, and *Lactobacillus bulgaricus*—combined with the prebiotic fructooligosaccharide (FOS). The product is designed to modulate the gut microbiota and restore healthy intestinal flora, particularly in infants and young children. Clinical studies have demonstrated its efficacy in reducing the severity of atopic dermatitis (AD), as measured by the SCORAD index, and it has also been investigated for its impact on anthropometric measurements and microbiota composition in pediatric obesity (Probesity-2 trial). It is typically administered as an oral freeze-dried powder.

Brand names: Protexin Restore

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