Drug intelligence / Profile preview

PRP Concepts Fibrin Bio-Matrix

Development stage
Discontinued
Lead developer
PRP Concepts
Administration
Topical
01

Overview

PRP Concepts Fibrin Bio-Matrix is an autologous platelet-rich fibrin matrix (PRFM) developed by PRP Concepts, LLC for the treatment of chronic, non-healing pressure ulcers. The product is generated from a patient's own peripheral blood, which is processed to create a concentrated fibrin scaffold that encapsulates platelets. Unlike traditional platelet-rich plasma (PRP), which is liquid and releases growth factors rapidly, the fibrin bio-matrix serves as a structural scaffold that facilitates the sustained, controlled release of endogenous growth factors, including platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-β), and vascular endothelial growth factor (VEGF). This localized delivery system promotes tissue repair, angiogenesis, and wound closure by providing a bioactive environment for cellular migration and regeneration within the wound bed.

Brand names
PRP Concepts Fibrin Bio-Matrix
Other names
platelet-rich fibrin matrixPRFMPRP Concepts PRFM
02

Targets

VEGFR (VEGFR family)PDGFR (PDGFR family)Fibrin (Factor Ia)TGFBR (TGF-beta receptor)

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