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PRRSExoVac
- Development stage
- Preclinical
- Lead developer
- Innovex Therapeutics
- Modality
- Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Vaccines & Immunotherapeutics
- Administration
- Intramuscular
01
Overview
PRRSExoVac (also referred to as PrrsvExoVac) is a preclinical-stage veterinary vaccine developed by Innovex Therapeutics for the prevention of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) infection in swine. The vaccine utilizes a novel modality consisting of serum-derived exosomes formulated with a Montanide adjuvant. Its mechanism of action involves leveraging these exosomes to induce robust humoral (antibody) and cellular (CD8+ T-cell) immune responses against PRRSV, a significant pathogen that causes substantial economic losses in the global swine industry.
- Other names
- PRRSExoVacPrrsvExoVac
02
Targets
B-cell receptor specific for Porcine Reproductive and Respiratory Syndrome Virus antigensTCR (T cell antigen receptor complex)Swine Leukocyte Antigen (SLA) class I and class II molecules presenting Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) peptides
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