Drug intelligence / Profile preview

PRRSV vaccine

Development stage
Preclinical
Lead developer
Ciloa
Modality
Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Vaccines & Immunotherapeutics
Administration
Intramuscular, Intradermal, Intranasal, Parenteral
01

Overview

Ciloa's PRRSV vaccine is an experimental veterinary biologic currently in preclinical development for the prevention of Porcine Reproductive and Respiratory Syndrome (PRRS). The vaccine utilizes Ciloa's proprietary small extracellular vesicle (sEV) platform, which involves engineering cells to secrete exosomes that display specific PRRSV antigens on their surface. This approach is designed to mimic the natural presentation of viral proteins to the immune system, potentially inducing a more effective and safer immune response compared to traditional live-attenuated or inactivated vaccines. The program is part of Ciloa's broader pipeline of sEV-based vaccines targeting both human and animal health.

02

Targets

GP5 (Porcine reproductive and respiratory syndrome virus glycoprotein 5)Porcine reproductive and respiratory syndrome virus nucleocapsid protein

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