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prunella vulgaris
- Development stage
- Unknown
- Lead developer
- Hospital of Chengdu University of Traditional Chinese Medicine
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
*Prunella vulgaris* is a perennial herb in the genus *Prunella*, widely used in Traditional Chinese Medicine (TCM) for its anti-inflammatory, antimicrobial, and immunomodulatory properties. In the context of thyroid health, it is primarily utilized to treat benign thyroid nodules and goiter. The mechanism of action is thought to involve the inhibition of thyroid cell proliferation and the modulation of inflammatory cytokines, potentially through the regulation of the TGF-beta/Smad signaling pathway or antioxidant effects. It is often formulated as tablets (Xiakucao Pian) or oral liquids for clinical use in China, where it is evaluated for its ability to reduce nodule size and improve clinical symptoms in patients with small benign nodules.
- Brand names
- Xiakucao PianPrunella Vulgaris Tablets
- Other names
- Self-healHeal-allXiakucaoXia Ku Cao
02
Targets
TGFB (GARP–latent transforming growth factor beta 1 complex)
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