Drug intelligence / Profile preview

PSC01

Development stage
Unknown
Lead developer
PersonGen BioTherapeutics
Modality
Gene Addition/Replacement → Gene Therapies, Gene Silencing → Gene Therapies, Gene Editing → Gene Therapies, CAR-T Cells → Engineered T Cells → Adoptive Cell Transfer → Cell Therapies
Administration
Intravenous
01

Overview

PSC01 is an investigational in vivo chimeric antigen receptor (CAR) T-cell therapy being developed by PersonGen for the treatment of B-cell malignancies. Utilizing an in vivo approach, PSC01 aims to genetically reprogram a patient's T cells to express a CAR targeting the CD19 antigen directly within the body, bypassing the need for the complex and time-consuming ex vivo manufacturing processes typical of traditional CAR-T therapies. This technology is designed to provide a more efficient and scalable treatment option for patients with CD19-positive cancers, such as B-cell lymphomas and leukemias.

Other names
PersonGen CD19 in vivo CAR-T
02

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