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pseudoginsenoside gq
- Development stage
- Phase 2
- Lead developer
- Jilin Huakang Pharmaceutical
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
Pseudoginsenoside GQ is a dammarane-type triterpene saponin isolated from the leaves of Panax species, specifically developed by Jilin Huakang Pharmaceutical for cardiovascular indications. It is primarily investigated for the treatment of stable angina pectoris and coronary heart disease. The compound exhibits significant cardioprotective properties, including the ability to improve myocardial ischemia, reduce myocardial oxygen consumption, and protect cardiomyocytes from oxidative stress and apoptosis. Clinical evaluation in China, particularly in its injectable form, has focused on its efficacy in relieving symptoms of chronic stable angina and improving cardiac function in patients with coronary heart disease.
- Other names
- Pseudoginsenoside GQ拟人参皂苷GQ
02
Targets
CACNA1C (Voltage-dependent L-type calcium channel subunit alpha-1C)LTCC (Voltage-gated calcium channel (L-type))
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