Drug intelligence / Profile preview

Psoralea corylifolia

Development stage
Phase 3
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Psoralea corylifolia is a medicinal plant widely used in traditional Chinese medicine (as 补骨脂) and Ayurveda (as bakuchi or babchi). The seeds and fruits are the primary medicinal parts. It contains bioactive compounds such as psoralen, isopsoralen, bakuchiol, bavachin, bavachalcone, corylin, and various flavonoids and coumarins. Traditionally it has been used for skin disorders (vitiligo, psoriasis), to promote bone health and calcification, as an aphrodisiac and rejuvenative tonic for kidney yang deficiency symptoms (e.g., lower back pain), to treat respiratory conditions like asthma and coughs, digestive issues including constipation and indigestion, urinary tract disorders including enuresis/bedwetting/frequent urination in elderly men or children. Modern research suggests antioxidant activity; anti-inflammatory; antibacterial; antifungal; immunomodulatory; estrogenic; anticancer properties. However there is no robust clinical evidence supporting its efficacy for any indication[3][7]. Oral use of supplements can cause severe hepatotoxicity[3]. In TCM it is considered warm in nature with actions to tonify kidney yang energy.

Brand names
Babuchi
Other names
babchibakuchiCullen corylifoliumPsoraleae Fructus补骨脂
02

Targets

CYP3A4 (Cytochrome P450 3A4)ER (Estrogen receptor)mAChR (Muscarinic acetylcholine receptors)TYR (Tyrosinase)MC1R (Melanocortin Type 1 Receptor)

Beyond the preview

Go deeper on Psoralea corylifolia.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Psoralea corylifolia.

Gosset Free

Get started with Gosset.

Enter your corporate email.

Work email preferred.

Book a call