Drug intelligence / Profile preview

Psorisome

Development stage
Unknown
Lead developer
Lifecare Innovations
Modality
Small Molecules, Liposomes → Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
Administration
Topical
01

Overview

Psorisome is a liposomal topical gel formulation of dithranol (also known as anthralin) developed by Lifecare Innovations in collaboration with the University Institute of Pharmaceutical Sciences at Panjab University. It is approved for the treatment of chronic psoriasis. The active ingredient, dithranol, acts by inhibiting DNA synthesis and keratinocyte proliferation, which slows the abnormally rapid skin cell turnover characteristic of psoriatic plaques. The liposomal delivery system (0.5% w/w) is designed to enhance the penetration of the drug into the skin while potentially reducing common side effects associated with conventional dithranol treatments, such as perilesional skin irritation and staining.

Brand names
Psorisome
Other names
Liposomal dithranolLiposomal anthralinLiposomal dithranol gel
02

Targets

DNA

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