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PT-106
- Development stage
- Preclinical
- Lead developer
- ProbioTech
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Rectal
01
Overview
**PT-106** is an investigational rectal suppository developed by ProbioTech for radiation-induced proctitis. It combines a live biotherapeutic product with antioxidants and is intended to locally modulate the rectal mucosal microbiome, restore microbial balance, and mitigate oxidative injury associated with radiation exposure. The program is IND-enabling, with FDA feedback on the clinical plan pending. ([probiotechusa.com](https://probiotechusa.com/))
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