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PT-108

Development stage: Preclinical
Lead developer: ProbioTech
Modality: Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration: Oral, Rectal

Overview

PT-108 is a ProbioTech prescription microbiome therapeutic candidate for recurrent Clostridioides difficile infection. It is described as a live biotherapeutic product containing health-promoting bacteria together with antioxidant components, intended for oral capsule and/or rectal suppository delivery to restore a healthier gut microbial ecosystem, strengthen colonization resistance against recurrent C. difficile, and mitigate inflammation. ProbioTech also identifies PT-108 within its patented PT-106/PT-107/PT-108 product family for microbiome-related gastrointestinal and women's-health applications. ([probiotechusa.com](https://probiotechusa.com/))

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