budesonide

Budesonide is a synthetic corticosteroid with potent anti-inflammatory properties. It acts primarily as a glucocorticoid receptor agonist and is used to treat various inflammatory diseases affecting the airways and gastrointestinal tract. Budesonide works by inhibiting multiple types of inflammatory cells (such as mast cells and eosinophils) and suppressing the release of inflammatory mediators like histamine and cytokines. It has high topical anti-inflammatory activity with minimal systemic effects due to extensive first-pass metabolism in the liver. Budesonide is indicated for conditions such as asthma (inhaled), chronic obstructive pulmonary disease (COPD), Crohn's disease (oral), ulcerative colitis (oral/rectal), eosinophilic esophagitis (oral suspension/tablet), primary immunoglobulin A nephropathy (oral delayed-release capsule), autoimmune hepatitis (oral capsule/granule), allergic rhinitis/nasal polyps (nasal spray), and microscopic colitis[1][2][3][4][5][6][7][8].

Brand names

PulmicortPulmicort FlexhalerPulmicort TurbuhalerPulmicort RespulesEntocort ECEohiliaOrtikosUcerisTarpeyoCortimentBudenofalkJorvezaRhinocort Aqua

Other names

budesónida