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PTC-2113

Development stage: Preclinical
Lead developer: Eos Senolytix
Modality: Peptides
Administration: Subcutaneous

Overview

PTC-2113 is a preclinical-stage mitochondrial-targeted geropeptide being developed by Eos Senolytix for the treatment of obesity and glucose metabolic disorders. Powered by the proprietary MitoXcel™ technology platform, PTC-2113 is designed to target the age-associated decline in mitochondrial membrane potential (MMP, ΔΨm). Specifically, PTC-2113 acts via 'Mechanism 1' of the platform, which rapidly restores mitochondrial efficiency in aging cells, shifting them toward a youthful energetic phenotype and enhancing ATP production. This approach aims to improve metabolic health and body composition without directly targeting muscle or fat regulatory pathways.

Targets

COX7C (Cytochrome c oxidase subunit 7C, mitochondrial)Mitochondrial electron transport chain Complex III proteins

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