Drug intelligence / Profile preview

PTC-2113

Development stage
Preclinical
Lead developer
Eos Senolytix
Modality
Peptides
Administration
Subcutaneous
01

Overview

PTC-2113 is a preclinical-stage mitochondrial-targeted geropeptide being developed by Eos Senolytix for the treatment of obesity and glucose metabolic disorders. Powered by the proprietary MitoXcel™ technology platform, PTC-2113 is designed to target the age-associated decline in mitochondrial membrane potential (MMP, ΔΨm). Specifically, PTC-2113 acts via 'Mechanism 1' of the platform, which rapidly restores mitochondrial efficiency in aging cells, shifting them toward a youthful energetic phenotype and enhancing ATP production. This approach aims to improve metabolic health and body composition without directly targeting muscle or fat regulatory pathways.

02

Targets

Mitochondrial electron transport chain Complex III proteinsCOX7C (Cytochrome c oxidase subunit 7C, mitochondrial)bc1 complex (Cytochrome bc1 complex (plasmodium))

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