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pterolobium stellatum crude hydromethanolic extract

Development stage
Preclinical
Lead developer
Arba Minch University
Modality
Small Molecules
Administration
Oral
01

Overview

Pterolobium stellatum crude hydromethanolic extract is a botanical research compound derived from the leaves of the Ethiopian medicinal plant *Pterolobium stellatum*. Traditionally used in Ethiopia for the treatment of seizures and epilepsy, the extract is prepared using 80% methanol and contains a complex mixture of phytochemicals, including gallic acid, ellagic acid, kaempferol, myricitrin, isoquercitrin, and quercitirin. Preclinical studies have demonstrated significant anti-seizure activity in both in vitro (0 Mg2+ mouse brain slice model) and in vivo (maximal electroshock and pentylenetetrazol-induced seizure) models. Additionally, the extract exhibits antimycobacterial properties against *Mycobacterium tuberculosis* and anti-nociceptive effects in animal models. It is currently being investigated by academic institutions, such as Arba Minch University, for its potential therapeutic applications in neurology and infectious diseases.

Other names
Pterolobium stellatum leaf extracthydromethanolic extract of Pterolobium stellatum

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