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PTx803
- Development stage
- Preclinical
- Lead developer
- Primal Therapies
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Small Molecules, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Topical
01
Overview
PTx803 is a preclinical-stage small molecule therapeutic being developed by Primal Therapies for the topical treatment of fungal overgrowth. It utilizes the company's proprietary SMMRT (Selective Microbial Metabolism Regulation Technology) platform, which is designed to selectively regulate microbial metabolism rather than acting as a broad-spectrum antimicrobial. By targeting specific metabolic pathways associated with fungal overgrowth, PTx803 aims to restore microbial balance. The drug is currently in the discovery and formulation development phase, with the sponsor developing it as a powder formulation intended for potential out-licensing.
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