Drug intelligence / Profile preview

Pudilan Keyanning mouthrinse

Development stage
Unknown
Lead developer
Jiangsu Pudilan Daily Chemical
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Topical
01

Overview

Pudilan Keyanning mouthrinse is a Traditional Chinese Medicine (TCM)-based oral care product developed for the management of dental plaque and gingivitis. The formulation is derived from the Pudilan formula, which typically consists of four medicinal herbs: *Scutellaria baicalensis* (Huangqin), *Taraxacum mongolicum* (Pugongying), *Corydalis bungeana* (Kudiding), and *Isatis tinctoria* (Banlangen). These components provide a synergistic effect characterized by anti-inflammatory, antibacterial, and antioxidant properties. The mouthrinse is designed to reduce gingival inflammation and inhibit the formation of dental plaque by targeting oral pathogens and modulating the local inflammatory response. It has been evaluated in Phase 4 clinical trials, including studies sponsored by the Peking University School of Stomatology, to compare its efficacy and safety against standard chemical mouthwashes like chlorhexidine.

Brand names
Pudilan KeyanningPudilan Keyanning mouthrinse
Other names
Pudilan Keyanning bacteriostatic mouthrinsePudilan mouthrinse

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