Drug intelligence / Profile preview

Pudilan oral liquid

Development stage
Unknown
Lead developer
Jichuan Pharmaceutical Group
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Pudilan oral liquid (also known as Pudilan Xiaoyan oral liquid) is a widely used commercial Traditional Chinese Medicine (TCM) / Chinese patent medicine in China. It is prepared from four cold-natured herbs: *Scutellaria baicalensis* (Huangqin), *Isatis indigotica* (Banlangen), *Corydalis bungeana* (Dihuding), and *Taraxacum mongolicum* (Pugongying). Pudilan oral liquid possesses heat-clearing, detoxifying, anti-inflammatory, and antibacterial properties. It is clinically indicated for the treatment of inflammatory and infectious conditions such as pharyngitis, tonsillitis, mumps, and upper respiratory tract infections. Additionally, it has been evaluated in clinical trials for pediatric COVID-19.

Brand names
Pudilan Xiaoyan Oral Liquid
Other names
PDLPudilan antiphlogistic oral liquidPudilan Xiaoyan KoufuyePudilan Xiaoyan oral liquid
02

Targets

ACE2 (Angiotensin-converting enzyme 2)TLR3 (Toll-like receptor 3)PI3K (Phosphoinositide-3-kinase regulatory subunit 6)MYD88 (Myeloid differentiation primary response protein MyD88)RK (Ribokinase)TLR4 (Toll-like receptor 4)NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)

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