pueraria candollei var. mirifica

Pueraria candollei var. mirifica is a medicinal plant native to Thailand, widely known in traditional medicine as "Kwao Krua" or "White Kwao Krua," and used for rejuvenation and relief of menopausal symptoms. Its tuber contains high concentrations of phytoestrogens, primarily miroestrol, deoxymiroestrol, puerarin, daidzein, daidzin, genistein, and other related compounds. These phytoestrogens exhibit estrogenic activity, preferentially binding to estrogen receptor beta (ERβ) and modulating gene expression in target tissues. Mechanistic studies show in vitro and animal models evidence for estrogen receptor agonism, antioxidant activity, potential bone protective effects, and mild neuroprotective effects. Clinical studies for postmenopausal symptom management show reduced hot flashes, improved urogenital symptoms, and reduced bone turnover, but results are inconclusive and further study is needed. Pueraria candollei var. mirifica is not approved as a pharmaceutical and is widely marketed as a dietary supplement for menopause relief and general rejuvenation[1][2][3][4][5][6].

Brand names

Kwao KruaKwao Krua Kao

Other names

Pueraria mirificaWhite Kwao KruaKwao Krua KaoAiry Shaw & Suvat. NiyomdhamPM