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Puerarin Phospholipids Complex Capsules
- Development stage
- Preclinical
- Lead developer
- PuraPharm
- Modality
- Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Small Molecules
- Administration
- Oral
01
Overview
Puerarin Phospholipids Complex Capsules is an oral pharmaceutical formulation developed by PuraPharm for the treatment of cardiovascular disorders. The drug consists of puerarin, a major bioactive isoflavone extracted from the root of *Pueraria lobata* (Kudzu), formulated as a phospholipid complex to overcome the natural compound's poor oral bioavailability and absorption. By utilizing this lipid-based delivery system, the formulation aims to enhance the therapeutic efficacy of puerarin in managing heart and vascular conditions. The product has received clinical trial approval from the China Food and Drug Administration (CFDA), marking its transition from traditional herbal use to a standardized clinical candidate.
- Other names
- 葛根素磷脂複合物膠囊puerarin phospholipid complexoral formulation of puerarin-phospholipid complex
02
Targets
PPARG (Peroxisome proliferator-activated receptor gamma)GABRR (GABA-A receptor subunit rho)AMPK (Adenosine monophosphate–activated protein kinase)PPARA (Peroxisome proliferator-activated receptor alpha)FXR (Farnesoid x-activated receptor)
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