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Puerarin Phospholipids Complex Capsules
- Development stage
- Preclinical
- Lead developer
- PuraPharm
- Modality
- Small Molecules, Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems
- Administration
- Oral
01
Overview
Puerarin Phospholipids Complex Capsules is an oral pharmaceutical formulation developed by PuraPharm for the treatment of cardiovascular disorders. The drug consists of puerarin, a major bioactive isoflavone extracted from the root of *Pueraria lobata* (Kudzu), formulated as a phospholipid complex to overcome the natural compound's poor oral bioavailability and absorption. By utilizing this lipid-based delivery system, the formulation aims to enhance the therapeutic efficacy of puerarin in managing heart and vascular conditions. The product has received clinical trial approval from the China Food and Drug Administration (CFDA), marking its transition from traditional herbal use to a standardized clinical candidate.
- Other names
- 葛根素磷脂複合物膠囊puerarin phospholipid complexoral formulation of puerarin-phospholipid complex
02
Targets
AMPK (Adenosine monophosphate–activated protein kinase)GABRR (GABA-A receptor subunit rho)PPARA (Peroxisome proliferator-activated receptor alpha)PPARG (Peroxisome proliferator-activated receptor gamma)
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