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Drug intelligence / Profile preview
PulmoProst (iloprost)
- Development stage
- Unknown
- Lead developer
- Infusyn Therapeutics
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
PulmoProst is a therapeutic product developed by Infusyn Therapeutics for the treatment of Pulmonary Arterial Hypertension (PAH). It involves the intravenous administration of iloprost, a synthetic analogue of prostacyclin, delivered via the Prometra II programmable infusion pump. Iloprost acts as a potent agonist of the prostacyclin (IP) receptor, which mediates vasodilation of the pulmonary and systemic arterial vascular beds and inhibits platelet aggregation. The PulmoProst program has completed a Special Protocol Assessment (SPA) with the FDA, facilitating the design of a pivotal clinical trial for PAH.
- Brand names
- PulmoProst
- Other names
- iloprost
02
Targets
PTGDR (Prostanoid DP1 receptor)PTGER1 (Prostaglandin E Receptor 1)PTGER2 (Prostaglandin E2 receptor EP2)PTGER3 (Prostaglandin E2 receptor EP3 subtype)PTGER4 (Prostaglandin E2 receptor EP4 subtype)PTGFR (Prostaglandin F2 alpha receptor)PTGIR (Prostanoid IP Receptor)
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