Drug intelligence / Profile preview

punica granatum skin extract

Development stage
Unknown
Lead developer
Zeus Hygia Life Sciences
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral, Topical
01

Overview

Punica granatum skin extract is a botanical extract derived from the skin (peel) of the pomegranate fruit. It is rich in various bioactive compounds, including polyphenols such as ellagic acid, punicalagin, gallic acid, anthocyanins, and flavonoids, as well as vitamins (C, B) and trace elements. This extract is recognized for its potent antioxidant, anti-inflammatory, and antimicrobial properties. It functions by neutralizing free radicals, reducing inflammatory responses, and inhibiting the growth of various microorganisms. Additionally, it has been shown to inhibit melanogenesis and tyrosinase activity, modulate collagen and hyaluronic acid metabolism, stimulate cellular renewal, and offer photoprotective effects against UV radiation. It is widely utilized in the cosmetic, skincare, and dietary supplement industries for its beneficial effects on skin health, including reducing wrinkles, improving skin radiance, elasticity, firmness, and addressing concerns like hyperpigmentation and acne.

Brand names
Grantria
Other names
Punica granatum extractPomegranate extract
02

Targets

TYR (Tyrosinase)MMP12 (Macrophage Metalloelastase)

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