Drug intelligence / Profile preview

Punjabi Univ. NOX2 compound ASP5

Development stage: Unknown
Lead developer: Punjabi University

Overview

Punjabi Univ. NOX2 compound ASP5: sourced facts only. name: "ASP1 showed the highest total NOX inhibition (IC50 4.69 ± 0.23 ng/mL), ASP5 was most selective for NOX2 (2.68 ± 0.10 ng/mL), and ASP20 exhibited highest NOX4 potency (127.77 ± 9.11 pg/mL)." [PMID:41711362]; target: "ASP1 showed the highest total NOX inhibition (IC50 4.69 ± 0.23 ng/mL), ASP5 was most selective for NOX2 (2.68 ± 0.10 ng/mL), and ASP20 exhibited highest NOX4 potency (127.77 ± 9.11 pg/mL)." [PMID:41711362]; developer: "Department of Pharmaceutical Sciences and Drug Research, Punjabi University, Patiala, India." [PMID:41711362]

Targets

NOX2 (NADPH oxidase 2)

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