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**Purell Hand Sanitizer** is a GOJO topical over-the-counter antiseptic product line used to reduce bacteria on the skin. The named product is not a single chemically uniform drug entity: PURELL formulations include gels, foams, and sprays, commonly using ethyl alcohol as the antimicrobial active ingredient at formulation-specific concentrations, including 70% in many Advanced Hand Sanitizer products and 85% in certain sprays. Ethanol acts as a broad, nonspecific topical antimicrobial by disrupting microbial membranes and denaturing proteins. A pilot clinical study evaluated Purell Hand Sanitizer for effects on lesion duration, pain, discomfort, and lesion size in herpes simplex virus type 1 infection; this investigational use does not establish an approved antiviral indication. ([gojo.com](https://www.gojo.com/en/Product-Catalog/Hand-Sanitizer-v2/Ingredient-Transparency))
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