Drug intelligence / Profile preview

purslane gel

Development stage
Unknown
Lead developer
Qionglai City Traditional Chinese Medicine Hospital
Modality
Small Molecules
Administration
Topical
01

Overview

Purslane gel is a topical herbal formulation developed by the Qionglai Hospital of Traditional Chinese Medicine for the treatment of acne vulgaris. The active ingredient is derived from *Portulaca oleracea* (purslane), a succulent plant widely used in traditional medicine for its anti-inflammatory, antimicrobial, and antioxidant properties. The gel works by reducing skin inflammation through the inhibition of pro-inflammatory cytokines and the suppression of the NF-κB signaling pathway. Additionally, it exhibits antimicrobial activity against common skin pathogens associated with acne, such as *Cutibacterium acnes*. As a hospital-specific preparation (医院制剂) in China, it is used as a localized therapeutic option to alleviate redness, swelling, and bacterial infection while promoting skin barrier repair.

Other names
Portulaca oleracea gelMachixian gelMachixian Ningjiao
02

Targets

TNFA (Tumor necrosis factor alpha (soluble))IL-6 (Interleukin 6)NF-κB

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