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Pushen

Development stage: Preclinical
Lead developer: Nanjing Drum-Tower Hospital
Administration: Oral

Overview

**Pushen** is an oral multi-herb traditional Chinese medicine capsule preparation. Published descriptions report a formula primarily comprising *Polygonum multiflorum*, *Pollen Typhae*, *Salvia miltiorrhiza*, *Ligusticum chuanxiong*, and paeoniflorin; an earlier patent description lists a narrower formula based on *Polygonum multiflorum*, *Pollen Typhae*, and *Salvia miltiorrhiza*. Its molecular mechanism has not been conclusively established. Clinical research has evaluated Pushen for vascular mild cognitive impairment and acute ischemic stroke, including the randomized, placebo-controlled ChiCTR2100052920 study in ischemic stroke. ([pmc.ncbi.nlm.nih.gov](https://pmc.ncbi.nlm.nih.gov/articles/PMC6862923/))

Other names: PushenPushen capsule蒲参胶囊

Targets

DRD2 (Dopamine D2 Receptor)ADORA2A (Adenosine A₂A Receptor)PPP1R1B (Protein phosphatase 1 regulatory inhibitor subunit 1B)MYC (MYC proto-oncogene protein)

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