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Drug intelligence / Profile preview
Pushen
- Development stage
- Phase 4
- Lead developer
- Nanjing Drum-Tower Hospital
- Administration
- Oral
01
Overview
**Pushen** is an oral multi-herb traditional Chinese medicine capsule preparation. Published descriptions report a formula primarily comprising *Polygonum multiflorum*, *Pollen Typhae*, *Salvia miltiorrhiza*, *Ligusticum chuanxiong*, and paeoniflorin; an earlier patent description lists a narrower formula based on *Polygonum multiflorum*, *Pollen Typhae*, and *Salvia miltiorrhiza*. Its molecular mechanism has not been conclusively established. Clinical research has evaluated Pushen for vascular mild cognitive impairment and acute ischemic stroke, including the randomized, placebo-controlled ChiCTR2100052920 study in ischemic stroke. ([pmc.ncbi.nlm.nih.gov](https://pmc.ncbi.nlm.nih.gov/articles/PMC6862923/))
- Brand names
- Pushen
- Other names
- PushenPushen capsule蒲参胶囊
02
Targets
ADORA2A (Adenosine A₂A Receptor)DRD2 (Dopamine D2 Receptor)PPP1R1B (Protein phosphatase 1 regulatory inhibitor subunit 1B)MYC (MYC proto-oncogene protein)HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)AMPK (Adenosine monophosphate–activated protein kinase)
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