pVAX plasmid DNA

pVAX plasmid DNA (specifically the pVAX1 plasmid vector) is an empty, non-antigen-encoding bacterial plasmid DNA construct used as a control or placebo comparator in clinical and veterinary trials. Developed under the auspices of the Queensland Institute of Medical Research (QIMR) and collaborating institutions, it has been evaluated in a Phase 3 trial in China as a control vaccine within an integrated schistosomiasis control program targeting *Schistosoma japonicum* transmission in bovines (water buffalo and cattle). The plasmid serves as the backbone vector for active DNA vaccines (such as SjCTPI-Hsp70 and SjC23-Hsp70) but is administered in its empty form to establish baseline immune responses and evaluate vaccine efficacy. It is typically manufactured to GLP standards by contract manufacturers like Aldevron.

Other names

pVAX1 plasmid DNApVAX-1 plasmid DNApVAX 1 plasmid DNApVAX controlempty pVAX1 plasmid