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PVT-005 is a preclinical small molecule anticancer drug candidate. It was part of a pipeline developed by IndUS Pharmaceuticals, which was acquired by Pivot Pharmaceuticals in 2015. The drug is designed to target refractory women's cancers, specifically metastatic endometrial cancer and basal-like-triple-negative breast cancer. Its mechanism of action is based on PBD dimers, which are known DNA alkylating agents.
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