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Pylorex plus
- Development stage
- Phase 3
- Lead developer
- The Islamia University of Bahawalpur
- Modality
- Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Pylorex plus is a polyherbal phytomedicine developed for the eradication of *Helicobacter pylori* infection and the relief of associated gastrointestinal symptoms such as dyspepsia and gastritis. The formulation consists of extracts from several plants, including *Glycyrrhiza glabra* (licorice), *Coriandrum sativum* (coriander), *Foeniculum vulgare* (fennel), *Elettaria cardamomum* (cardamom), and *Zingiber officinale* (ginger). It has been evaluated in clinical trials in Pakistan, notably a Phase 2/3 randomized trial comparing its efficacy to standard bismuth-based quadruple therapy. The drug is intended to provide a safer, herbal alternative to conventional antibiotics, leveraging the antimicrobial and gastroprotective properties of its botanical constituents.
- Brand names
- Pylorex plus
- Other names
- Pylorex plus consisting of medicinal plants
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