Drug intelligence / Profile preview

pyracantha fortuneana extract

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Pyracantha fortuneana extract is derived from the fruit of Pyracantha fortuneana (Chinese firethorn), a plant traditionally used in Chinese medicine and as a functional food. The extract contains a variety of bioactive compounds including proanthocyanidins, phenolic acids, flavonoids, polysaccharides, tannins, organic acids, and natural pigments[1][6][8]. It exhibits multiple pharmacological activities such as antioxidant effects (scavenging free radicals and enhancing endogenous antioxidant enzymes like SOD and GPx), anti-inflammatory activity (modulating cytokines such as TNF-α), immune regulation, blood lipid-lowering effects, α-glucosidase inhibition (potentially beneficial for type 2 diabetes management), protection against renal toxicity (notably cadmium-induced injury), modulation of gut microbiota composition and function in metabolic disorders/obesity models[1][4][7]. Mechanistically, its actions are linked to upregulation of Nrf2/Keap1 pathway proteins involved in cellular defense against oxidative stress. The main routes of administration studied are oral supplementation or dietary inclusion. Pyracantha fortuneana extracts are also used in cosmetics for their antioxidative properties[3]. No specific pharmaceutical developer or manufacturer is identified; it is primarily available as a dietary supplement or functional food ingredient.

Other names
pyracantha fortuneana fruit extractChinese firethorn extractPFE
02

Targets

Sucrase-IsomaltaseMisfolded SOD1GPX4 (Glutathione peroxidase 4)TYR (Tyrosinase)

Beyond the preview

Go deeper on pyracantha fortuneana extract.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on pyracantha fortuneana extract.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call