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Drug intelligence / Profile preview
pyrithione zinc
- Development stage
- Phase 2
- Lead developer
- Lonza
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Pyrithione zinc is an active antimicrobial compound used primarily to treat dandruff and seborrheic dermatitis of the scalp. It has antibacterial, antimicrobial, and antifungal properties that help control the symptoms of these conditions. The compound was rationally developed, modeled after the naturally occurring antimicrobial aspergillic acid. Its efficacy stems from its broad antimicrobial spectrum of activity against fungi, gram-positive and gram-negative bacteria, combined with its low solubility. This low solubility results in formulation as a particulate material that deposits and is retained on skin surfaces, functioning as slow-release reservoirs to provide extended and persistent benefits.
- Brand names
- ZinconBeta MedDermaZincDHS ZincSkincureZnPNeutrogena T/Gel Daily ControlSelsun Blue ConditionerHead & Shoulders Men AdvancedHead & Shoulders Old SpiceNoble FormulaVanicream Z-BarX-Seb PlusXolegel Duo
- Other names
- zinc pyrithioneZPT
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