Drug intelligence / Profile preview

pyrroloquinoline quinone disodium salt

Development stage
Unknown
Lead developer
Mitsubishi Gas Chemical
Modality
Small Molecules
Administration
Oral
01

Overview

Pyrroloquinoline quinone (PQQ) disodium salt is a redox-active cofactor and nutraceutical ingredient developed and manufactured by Fujian Comhony Biotechnology. As a small molecule, PQQ serves as a potent antioxidant and a key regulator of cellular energy metabolism. Its primary biological role involves the stimulation of mitochondrial biogenesis, largely through the activation of the peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1α) signaling pathway. By enhancing the production and function of mitochondria, PQQ is marketed for its potential benefits in supporting cognitive health, cardiovascular function, and overall cellular longevity. It is commonly utilized as a bulk ingredient in the formulation of dietary supplements.

Other names
PQQ disodium saltPyrroloquinoline quinone disodium saltmethoxatin disodium salt4,5-dihydro-4,5-dioxo-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid disodium salt
02

Targets

CREB (Cyclic AMP response element-binding protein)PPARGC1A (Peroxisome proliferator–activated receptor gamma coactivator 1-alpha)

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