Drug intelligence / Profile preview

QB-PCSK9207-223

Development stage: Preclinical
Modality: Split/Subunit Vaccines → Inactivated Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics, Cancer Vaccines → Therapeutic Vaccines → Vaccines & Immunotherapeutics, Recombinant Protein Vaccines → Recombinant Vaccines → Prophylactic Vaccines → Vaccines & Immunotherapeutics
Administration: Intramuscular

Overview

QB-PCSK9207-223 is a virus-like particle (VLP)-based vaccine designed to lower cholesterol by targeting Proprotein convertase subtilisin/kexin type 9 (PCSK9). PCSK9 is a secretory protein that regulates cholesterol homeostasis by promoting the degradation of low-density lipoprotein receptors (LDL-R). By inducing high-titer IgG antibodies that bind to circulating PCSK9, this vaccine aims to reduce PCSK9 activity, thereby decreasing total cholesterol, free cholesterol, phospholipids, and triglycerides. It is being investigated as an alternative to monoclonal antibody-based therapies for hypercholesterolemia, atherosclerosis, and cardiovascular disease.

Targets

PCSK9 (Proprotein convertase subtilisin/kexin type 9)

Beyond the preview

Go deeper on QB-PCSK9207-223.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on QB-PCSK9207-223.

Explore the full profile