QDose inhaled insulin

QDose inhaled insulin is a spray-dried formulation of recombinant human insulin developed by QDose Limited for the treatment of diabetes mellitus. It is designed for pulmonary administration via a dry powder inhalation device, providing a non-invasive alternative to subcutaneous insulin injections. The spray-drying process produces fine particles optimized for deep lung deposition and rapid systemic absorption across the alveolar-capillary membrane. Clinical development, including Phase 1 euglycemic clamp studies, has focused on evaluating its pharmacokinetic and pharmacodynamic profiles, specifically comparing its onset of action and glucose-lowering efficacy to standard subcutaneous regular human insulin.

Other names

Spray-dried recombinant human insulin powder for inhalationInhaled recombinant human insulin