Drug intelligence / Profile preview

QDP301

Development stage
Preclinical
Lead developer
RestoriT
Modality
Small Molecules
Administration
Oral, Sublingual
01

Overview

QDP301 is an investigational drug candidate being developed by RestoriT for the treatment of muscle spasms. It is a proprietary formulation of cyclobenzaprine hydrochloride utilizing the company's Quick Dissolve Platform (QDP), which is designed to facilitate rapid oral or sublingual disintegration and absorption. By bypassing first-pass metabolism and providing a faster onset of action than traditional oral tablets, QDP301 aims to provide more efficient relief for acute muscle spasms. Cyclobenzaprine, the active ingredient, is a skeletal muscle relaxant that acts primarily on the locus coeruleus in the brain stem, where it antagonizes 5-HT2 receptors to reduce tonic somatic motor activity. The asset is currently part of RestoriT's clinical pipeline targeting musculoskeletal conditions.

Other names
QDP301-RestoriT-muscle spasmQDP-301-RestoriT-muscle spasmQDP 301-RestoriT-muscle spasm
02

Targets

HRH1 (Histamine H1 Receptor)5-HT2 (5-HT2 receptor family)

Beyond the preview

Go deeper on QDP301.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on QDP301.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call