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QDP301 is an investigational drug candidate being developed by RestoriT for the treatment of muscle spasms. It is a proprietary formulation of cyclobenzaprine hydrochloride utilizing the company's Quick Dissolve Platform (QDP), which is designed to facilitate rapid oral or sublingual disintegration and absorption. By bypassing first-pass metabolism and providing a faster onset of action than traditional oral tablets, QDP301 aims to provide more efficient relief for acute muscle spasms. Cyclobenzaprine, the active ingredient, is a skeletal muscle relaxant that acts primarily on the locus coeruleus in the brain stem, where it antagonizes 5-HT2 receptors to reduce tonic somatic motor activity. The asset is currently part of RestoriT's clinical pipeline targeting musculoskeletal conditions.
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