Drug intelligence / Profile preview

QEQ278

Development stage
Phase 1
Lead developer
Novartis
Modality
Small Molecules
Administration
Intravenous
01

Overview

QEQ278 is an investigational intravenous drug candidate developed by Novartis for the treatment of advanced and metastatic solid tumors, including non-small cell lung cancer, esophageal squamous cell carcinoma, renal cell carcinoma, and human papilloma virus (HPV)-associated head and neck squamous cell carcinoma. It is currently being evaluated in phase 1 clinical trials to assess its safety, tolerability, pharmacokinetics, pharmacodynamics, and preliminary anti-tumor activity in adult patients who have exhausted standard therapy options or are ineligible for them. The precise mechanism of action of QEQ278 has not been disclosed as of now.

02

Targets

NKG2DL (NKG2D ligand family)

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