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Qi-Shao-Tong-Mai-An-Shen Decoction
- Development stage
- Unknown
- Lead developer
- China-Japan Friendship Hospital
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Qi-Shao-Tong-Mai-An-Shen Decoction is a Traditional Chinese Medicine (TCM) formula developed by the China-Japan Friendship Hospital specifically for the treatment of psycho-cardiological disorders, often referred to as "Double Heart Disease." This condition involves coronary heart disease (CHD) comorbid with psychological symptoms such as anxiety and depression. The decoction is formulated based on TCM principles to tonify Qi, nourish blood, promote blood circulation to unblock the meridians, and soothe the nerves to calm the mind. Its primary herbal components typically include *Astragalus membranaceus* (Huangqi) and *Paeonia lactiflora* (Baishao), which are combined with other herbs like *Salvia miltiorrhiza* and *Ziziphus jujuba* to address both the physical cardiovascular pathology and the associated emotional distress. Clinical studies suggest it improves cardiac function, reduces myocardial ischemia, and alleviates psychological symptoms by modulating the neuroendocrine-immune system and reducing systemic inflammation.
- Other names
- Qishao Tongmai Anshen Decoction芪芍通脉安神汤
02
Targets
NET (Norepinephrine Transporter)5-HT (Serotonin receptors)
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