Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
qiangxinyin
- Development stage
- Preclinical
- Lead developer
- Longhua Hospital Shanghai University of Traditional Chinese Medicine
- Administration
- Oral
01
Overview
Qiangxinyin (QXY) is a traditional Chinese medicine formula that has been investigated for the treatment of heart failure. A preclinical study demonstrated its effectiveness in protecting against isoproterenol-induced cardiac hypertrophy and dysfunction in zebrafish and cardiomyocyte models. [6] The formula's mechanism is thought to involve blocking calcium influx, reducing oxidative stress by lowering malondialdehyde (MDA) levels, stimulating ATP production, and increasing mitochondrial membrane potential. [6] Key active ingredients identified within the formula that contribute to these cardioprotective effects include psoralen (PRN), kaempferol (KMP), and icariin (ICA). [6] Mechanistically, Qiangxinyin enhances the phosphorylation of SMAD2 and MYPT1 while suppressing the phosphorylation of the myosin light chain. [6]
- Other names
- Qiangxinyin formula强心饮颗粒
02
Targets
MLC (Myosin light chain)CaV (Voltage-gated calcium channel protein complex)MYPT1 (Myosin phosphatase target subunit 1)SMAD2 (Mothers against decapentaplegic homolog 2)
Beyond the preview
Go deeper on qiangxinyin.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on qiangxinyin.