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Qidong Huoluo Granule
- Development stage
- Preclinical
- Lead developer
- Ruijin Hospital
- Administration
- Oral
01
Overview
Qidong Huoluo Granule is a traditional Chinese medicine (TCM) compound formulated as a granule, containing ingredients such as Astragalus, Ophiopogon, and other herbs. It is designed by a research team affiliated with traditional medicine in China and administered orally, typically twice daily[1][4]. The compound is used adjunctively in amyotrophic lateral sclerosis (ALS) and has been studied in combination with electroacupuncture. Its purported benefits include stabilization of symptoms related to bulbar paralysis, improvements in swallowing, speech, articulation, and breathing in ALS patients[1][2][4]. Mechanistically, although the precise pharmacological action is not well characterized by modern standards, it is believed to work via antioxidative and anti-inflammatory effects, possibly mitigating neurodegeneration and oxidative stress, and supporting neuronal health through effects observed in metabolomic and gut microbiota studies[4]. The formula does not represent a single chemical entity but rather a multi-herb mixture typical of TCM compounds.
- Brand names
- Qidong Huoluo Granule
- Other names
- Qidong Huoluo granuleQidong Huoluo granules
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