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Qigui Yishen Recipe
- Development stage
- Preclinical
- Lead developer
- First Affiliated Hospital of Soochow University
- Administration
- Oral
01
Overview
Qigui Yishen Recipe is a Traditional Chinese Medicine (TCM) compound preparation primarily investigated for its potential to delay the progression of chronic kidney disease (CKD), particularly renal fibrosis. It is recognized for its traditional functions of invigorating the kidney and spleen, enhancing qi, and stimulating blood circulation. Network pharmacology studies indicate that its therapeutic effects are mediated by active ingredients such as sitosterol, stigmasterol, mannitol, and quercetin. These components are believed to contribute to anti-inflammatory and anti-fibrotic actions, thereby reducing inflammation-induced kidney damage and preventing renal fibrosis. The preparation has been associated with a national patent (Patent No. ZL201310069692.0).
- Other names
- Qigui Yishen decoctionChinese Medicine Treatment
02
Targets
COL1 (Collagen type I)PAI-1 (Plasminogen activator inhibitor type 1)THBD (Thrombomodulin)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)
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