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Qihuang Jiangtang Jiaonang (also known as Qihuang Jiangtang Capsule or QHJTC) is a multi-component Traditional Chinese Medicine (TCM) formulation approved by the China Food and Drug Administration (CFDA) in 2017 for the treatment of type 2 diabetes mellitus (T2DM). Marketed under the brand name Yidaokang, it is specifically indicated for patients presenting with Qi and Yin deficiency and heat syndrome. The formulation is composed of various herbal ingredients, including Astragalus membranaceus and Polygonatum sibiricum, which work synergistically to regulate glucose metabolism, enhance insulin signaling, and reduce levels of inflammatory cytokines and reactive oxygen species. Network pharmacology studies have identified potential targets such as AKT1, TNF, and IL-6, suggesting a multi-pathway mechanism of action to improve insulin resistance and protect pancreatic function. It is typically administered orally as an adjunct to standard therapies like metformin.
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