Drug intelligence / Profile preview

Qing Bu Gong Xia Fang

Development stage
Unknown
Administration
Oral
01

Overview

Qing Bu Gong Xia Fang (清补攻下方) is a traditional Chinese medicine (TCM) formula. The name translates roughly as "Clear, Tonify, Attack, and Drain Formula," suggesting a combination approach of clearing pathogenic factors, supplementing deficiencies, attacking pathogens directly, and promoting elimination from the body. This type of formula is typically used in TCM for complex or chronic conditions where there is both deficiency (requiring tonification) and excess/pathogenic factors (requiring purgation or elimination). While the specific herbal composition and clinical indications for this exact formula are not found in standard English-language TCM references or major herbal compendia based on available sources, its structure implies use in cases involving mixed patterns such as chronic infections with underlying weakness or immune deficiency. Mechanistically, such formulas often combine herbs that clear heat/toxins (antimicrobial/anti-inflammatory), tonics that support qi/blood/yin/yang (immunomodulatory/nourishing), and purgatives to expel accumulations.

Brand names
Qing Bu Gong Xia Fang
Other names
清补攻下方
02

Targets

HIF1A (Hypoxia-inducible factor 1-alpha)ESR1 (ERα)HSP90AA1 (Heat shock protein HSP90-alpha)EGFR T790M (Epidermal growth factor receptor T790M mutant)IL-6 (Interleukin 6)CASP3 (Caspase-3)

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