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qing gan jie yu herbal formula granule
- Development stage
- Unknown
- Lead developer
- Dongzhimen Hospital of Beijing University of Traditional Chinese Medicine
- Administration
- Oral
01
Overview
Qing Gan Jie Yu Herbal Formula Granule (also known as Qinggan Jieyu decoction or QGJY) is a traditional Chinese medicine (TCM) herbal formula developed by the Department of Neurology at Dongzhimen Hospital, Beijing University of Traditional Chinese Medicine [ChiCTR-TRC-14004469]. It is formulated to treat liver meridian stagnant heat syndrome (liver depression of heat syndrome) presenting as migraine, non-organic insomnia, or anxiety [ChiCTR-TRC-14004469]. The formula consists of several Chinese herbal medicines, including Chaihu (*Radix Bupleuri Chinensis*), Huangqin (*Radix Scutellariae Baicalensis*), Yujin (*Radix Curcumae Wenyujin*), Zhuru (*Caulis Bambusae in Taeniam*), Jili (*Fructus Tribuli*), and Mohanlian (*Herba Ecliptae prostratae*). In clinical trials, it has demonstrated efficacy in improving sleep quality, sleep duration, and psychological health, as well as reducing migraine frequency and severity, potentially by downregulating purinergic receptor P2X7R expression and suppressing microglial activation and autophagy.
- Other names
- QGJY Herbal Formula GranuleQinggan Jieyu decoctionQinggan Jieyu granuleQingganJieyu Herbal Formula Granule清肝解郁方清肝解郁颗粒
02
Targets
CGRP (Calcitonin gene-related peptide)P2RX7 (P2X purinoceptor 7)SP (Substance P)
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