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This combination therapy consists of the traditional Chinese medicine (TCM) Qing Re Jie Du decoction and the proprietary Kai-Hou-Jian spray. It is primarily used in China for the treatment of hand, foot, and mouth disease (HFMD), particularly in pediatric patients. Qing Re Jie Du decoction is a herbal formula designed to clear heat and detoxify, often containing ingredients like honeysuckle and forsythia to address systemic viral symptoms and fever. Kai-Hou-Jian spray is a topical TCM formulation applied to the oral mucosa to relieve throat pain, reduce inflammation, and promote the healing of oral ulcers associated with HFMD. Research conducted by institutions like Beijing Youan Hospital has evaluated this combination's efficacy in reducing fever duration and accelerating the disappearance of skin and oral lesions.
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