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Qing-shang-fang-fen-tang (QSFFT) is a traditional Chinese herbal medicine (TCM) formula primarily utilized in dermatology for inflammatory conditions of the head and face. Traditionally indicated for clearing 'Wind-Heat' from the upper burner, it is frequently prescribed for acne vulgaris, facial flushing, and chronic urticaria. The formula typically consists of 12 herbal ingredients, including *Saposhnikovia divaricata* (Fangfeng), *Scutellaria baicalensis* (Huangqin), *Forsythia suspensa* (Lianqiao), and *Gardenia jasminoides* (Zhizi). These components provide a synergistic effect characterized by anti-inflammatory, antimicrobial, and anti-allergic activities. Clinically, it has been studied as an adjuvant or standalone therapy for refractory chronic urticaria, often demonstrating the ability to reduce symptom severity and improve quality of life when combined with other formulas like Xiao-feng-san.
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