Drug intelligence / Profile preview

Qingfei Granule

Development stage
Phase 1
Lead developer
Jilin Aodong Taonan Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Qingfei Granule is a traditional Chinese medicine (TCM) herbal formulation in granule form, used primarily for the treatment of acute upper respiratory tract infections, especially in pediatric populations. It is designed to relieve symptoms such as fever, sore throat, cough, and nasal congestion associated with wind-heat syndrome according to TCM principles. The formulation consists of multiple herbal ingredients (specific composition not detailed in the available sources), and it is intended as an alternative or adjunct to antibiotics for bacterial upper respiratory tract infections due to concerns about antibiotic resistance. Clinical studies are ongoing to assess its antibacterial effects and symptom relief efficacy in children with acute upper respiratory tract infection[6][7]. The mechanism of action is presumed multi-targeted based on TCM theory—likely involving anti-inflammatory and immunomodulatory effects—but specific molecular targets are not defined.

Brand names
Qingfei Granule
Other names
Qingfei Keli清肺颗粒
02

Targets

VEGFR2 (Vascular endothelial growth factor receptor 2)Spike-ACE2 PPI (SARS-CoV-2 spike–ACE2 interface)MMP2 (Matrix metalloproteinase-2)EGFR (Epidermal growth factor receptor)AR (Adrenergic receptors)ESR1 (ERα)

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