Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
qingfei paidu granule
- Development stage
- Unknown
- Lead developer
- Institute of Basic Research in Clinical Medicine, China Academy of Chinese Medical Sciences
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Qingfei Paidu granule is a standardized Traditional Chinese Medicine (TCM) pharmaceutical formulation developed for the treatment of COVID-19. It is derived from the 'Qingfei Paidu Decoction,' which integrates four classic prescriptions from the Han Dynasty's 'Treatise on Febrile Diseases' (Shanghan Lun): Maxing Shigan Decoction, Shegan Ma Huang Decoction, Xiao Chaihu Decoction, and Wuling Powder. The granule contains extracts from 21 medicinal herbs, including Ephedra, Licorice, and Bitter Almond. Its mechanism of action is multi-faceted, involving the inhibition of viral entry by targeting the ACE2 receptor, suppression of viral replication via 3CLpro inhibition, and mitigation of the 'cytokine storm' by modulating inflammatory pathways such as IL-6 and TNF-alpha signaling. It was widely deployed in China across all stages of COVID-19 infection and received emergency approval and subsequent marketing authorization from the National Medical Products Administration (NMPA).
- Brand names
- Qingfei Paidu Granules
- Other names
- Qingfei Paidu Decoction清肺排毒颗粒清肺排毒汤
02
Targets
Mpro (3C-like proteinase of SARS-CoV-2)ACE2 (Angiotensin-converting enzyme 2)IL-6 (Interleukin 6)
Beyond the preview
Go deeper on qingfei paidu granule.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on qingfei paidu granule.