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Qingfei Zhisou is a Traditional Chinese Medicine (TCM) formulation primarily utilized for treating post-infection cough (PIC) and phlegm-heat lung cough, particularly in pediatric populations. The formulation is available in several dosage forms, most notably as a syrup (Children's Qingfei Zhisou Syrup) and a topical patch (Qingfei Zhisou Tie). It is composed of a complex mixture of nine primary herbs, including Indigo naturalis, Gypsum fibrosum, Fritillariae cirrhosae bulbus, Sinomenii caulis, Borneolum syntheticum, Bambusae concretio silicea, Meretricis concha, Rhei radix et rhizoma, and Glycyrrhizae Radix et rhizoma. The therapeutic profile of Qingfei Zhisou is characterized by its ability to clear heat, resolve phlegm, and alleviate coughing. Research involving network pharmacology and molecular docking has explored its potential mechanisms, suggesting it may modulate inflammatory pathways and immune responses to manage respiratory symptoms.
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